$131 Booking Denver to Indianapolis Flights: Key Details on Fares, Airlines, and Flight Schedules

The Denver to Indianapolis route offers year-round nonstop and connecting flight service. Frontier Airlines, Southwest Airlines, and United Airlines operate nonstop flights between Denver International Airport (DEN) and Indianapolis International Airport (IND), with travel times of about two hours 15 minutes to two hours 36 minutes. American and Delta operate connecting flights. Travelers can choose between the airlines, opting for either a low-fare or a full-service experience.

Denver to Indianapolis Flight Route Details

The DEN to IND route offers 42 to 52 nonstop flights per week. Indianapolis follows Eastern Time, which is UTC-5 during standard time and UTC-4 during daylight saving time. That puts the city two hours ahead of Denver, which is in the Mountain Time Zone. So if your flight departs at 8:00 a.m. and takes two hours and 15 minutes, you will land at 12:15 p.m. Indianapolis time.

The table below highlights other key details about the Denver to Indianapolis flight route.

The fares mentioned are based on CheapFlightsFares internal data.

Denver Airports for Indianapolis Flights

Denver International Airport (DEN) is the only airport in the area that handles commercial passenger flights to Indianapolis. Located 18-19 miles from downtown, the airport is well connected to the RTD A Line commuter rail, rideshare, taxis, and shuttle services.

The three airlines on this route operate primarily from Concourse A (Frontier), B (United), and C (Southwest). The airport also serves as a United Airlines hub and a base of operations for Frontier Airlines and Southwest Airlines.

DEN is one of the largest airports in the world, so plan your itinerary wisely. Arrive at least 2 to 3 hours before your departure to complete check-in, drop off baggage, and go through security without the risk of missing your flight.

How Much Does a Flight from Denver to Indianapolis Cost?

Based on CheapFlightsFares' fare trend for Denver to Indianapolis flights booked 30 days in advance from October 2026, the typical range is $131 to $178. The same range holds steady throughout the winter season, from November through February. This is the cheapest time to book flights from Denver to Indianapolis, excluding the holiday period. Winters usually see low tourism because of school breaks and the cold season.

The rush returns in December for Christmas and New Year's. Fares usually start at $195 and reach $331 around Christmas and New Year’s as many head home or visit family. Fares typically ease in mid-January once holiday travel ends and drop back into the normal winter range.

In spring, March through May flights range from $250 to $263 one way. The season is roughly $70 to $90 more than winter. Late May fares may be higher than the rest of spring because of Memorial Day weekend and the Indianapolis 500. June through September is the most expensive time, with fares ranging from $263 to $438. Family vacations, school breaks, and big Indianapolis events keep demand high.

Fares are subject to change.

How Long Is the Flight From Denver to Indianapolis?

A nonstop flight from Denver (DEN) to Indianapolis (IND) takes an average of two hours 15 minutes to two hours 36 minutes. Southwest lists an average of two hours 22 minutes, while other schedule data puts it closer to two hours 40 minutes. The gap comes from the airline, aircraft, and the day's winds.

Connecting itineraries add a stop, usually at a major hub such as Chicago, Dallas, Atlanta, or Charlotte. Total travel time depends on the layover, ranging from four hours and 40 minutes to more than six hours. A connection only makes sense when it saves real money.

Which Airlines Fly from Denver to Indianapolis?

About 42 to 52 weekly nonstop flights fly from Denver to Indianapolis, averaging about seven a day. This varies, depending on seasonal schedules. That means a nonstop departure every few hours for most of the day, from early morning to late evening. Frontier Airlines, Southwest Airlines, and United Airlines all operate nonstop service on the route.

Southwest Airlines

Southwest runs the most number of nonstop flights from Denver to Indianapolis. There are about three to five nonstop flights per day, but the schedule varies throughout the week. The average weekly schedule totals approximately 23 flights. Southwest uses Boeing 737s on the route and follows its standard baggage policy, which includes one carry-on bag and one personal item per ticketed passenger.

United Airlines

United operates two to three nonstop flights per day on the route, or about 14 a week. Denver International is one of United's major hubs. This means if you miss a flight, it's easier to rebook here than on most carriers. It flies Boeing 737 and Airbus A320 family aircraft between the two cities. Base fares generally include only a personal item, while a carry-on bag may require a higher fare.

Frontier Airlines

Frontier only flies one daily nonstop flight, with an average of seven nonstop flights a week. This makes availability low, especially at low-cost fares. The base price excludes carry-on bags, checked bags, and seat selection. Compare the total cost with extras added before booking. Frontier flies Airbus A320neo and A321 aircraft on this route.

Frequently Asked Questions

Is there a nonstop flight from Denver to Indianapolis?

Yes. Frontier, Southwest, and United operate approximately seven to nine nonstop flights a day. The exact number may vary by season.

How long is a flight from Denver, CO to Indianapolis?

A nonstop flight from Denver (DEN) to Indianapolis (IND) takes approximately two hours and 15 minutes to two hours and 36 minutes.

What is the time difference between Denver and Indianapolis?

Indianapolis is in Eastern Time (ET), two hours ahead of Denver, which is in Mountain Time (MT).

When is the cheapest time to book flights to Indianapolis?

The cheapest time to fly from Denver to Indianapolis is generally November through February, when fares typically run $131 to $178 for tickets booked about 30 days ahead.

Which airline is best for flying from Denver to Indianapolis?

While Southwest runs the most flights from Denver to Indianapolis, United has its hub at Denver Airport. If you miss a flight, it's generally easier to rebook with United at the airport. However, the best option depends on which airline offers the cheapest fare and great service.